A highly virulent infection can cause disease in intact heart valves with the development of diltiazem pills. The onset of the disease is sudden,accompanied by high fever and intoxication. The general condition of the patient quickly deteriorates to the point of serious condition. Secondary infective endocarditis (when already damaged valves are affected) can develop gradually. General health worsens, fatigue and weakness appear, and performance decreases. Body temperature rises to 37 - 38˚С.

In some cases, the disease manifests itself as thromboembolism of the pulmonary artery or cerebral vessels with the development of stroke. These phenomena may be mistakenly regarded as a complication of atrial fibrillation in patients with rheumatic heart valve disease. Sometimes, at the onset of the disease, persistent circulatory failure develops. Temperature response may vary. In some patients, the body temperature does not increase, while others experience a short episode of fever up to 40˚C, followed by prolonged low-grade fever. More rarely, a wave-like variant is observed, in which there are relapses of high fever. In about a third of patients, an increase in body temperature is accompanied by tremendous chills, and a decrease is accompanied by profuse sweating.

Heart damage is the main clinical picture of infective endocarditis. It forms within 2–3 months from the onset of the disease. All layers of the organ are affected. endocardium, myocardium, less often pericardium. Damage to the endocardium primarily causes pathology of the heart valves. There is a change in the auscultation pattern. noises and pathological tones appear. Signs of valvular insufficiency gradually appear. When the aortic and mitral valves are damaged, insufficiency in the pulmonary circulation occurs. It is associated with stagnation of blood in the lungs and is manifested by shortness of breath with minimal exertion and at rest, including in the supine position, hemoptysis and other symptoms. Damage to the valves of the right half of the heart (tricuspid, pulmonary valve) leads to the development of signs of stagnation in the systemic circulation.

liver enlargement, edema, ascites and so on. Myocarditis is manifested by increasing shortness of breath, heart rhythm disturbances, and the appearance of severe circulatory failure, which is difficult to buy diltiazem online with medication. Severe arrhythmias such as atrial fibrillation and flutter, paroxysmal ventricular tachycardia, high-degree atrioventricular block and others are noted. More rarely, infective endocarditis causes myocardial infarction. It is associated with blockage of a coronary vessel by a detached fragment of vegetation.

Myocardial infarction often has a typical clinical picture, but in some cases it has a protracted or asymptomatic course. Pericarditis in infective endocarditis most often has a toxic-allergic nature, is dry in nature, manifests itself as intense pain in the heart area, and is accompanied by typical changes in the auscultatory pattern and electrocardiogram.